As antipsychotic indications have spread, more patients are taking them in combination with their opposite: a stimulant. We look at the risks, search for scenarios where it might make sense, and come up with an action plan for this paradoxical pairing.

Numerous studies have established the efficacy of cognitive behavioral therapy (CBT) for a variety of psychiatric diagnoses. How effective CBT can be when delivered on a computer is an ongoing area of study. Here, researchers find that an internet-based CBT protocol was a helpful adjunctive treatment in a residential setting.

Problematic gambling is quite common, but many patients never receive any treatment. Hypothesizing that part of the reason for this is a lack of accessibility, researchers investigated the utility of internet-based gambling treatments. While not as effective as in-person treatment, the results were promising.

The hunt continues for effective medications for alcohol use disorder. Researchers here investigated the potential utility pioglitazone, a medication commonly used for diabetes management. 

Patients with alcohol-associated liver disease have traditionally needed to demonstrate an ability to refrain from drinking for 6 months before being deemed eligible for a liver transplant, despite the absence of research findings to support this requirement. Findings from this retrospective study show that a waiting period is not associated with improved outcomes. 

Supervised Consumption Sites are clinical settings where patients can use drugs in as safe a manner as possible. Clients are supplied with sterile equipment and the clinics are staffed by medical professionals who can respond in the case of an overdose. Once controversial, research clearly shows the benefit of these sites, and they have started opening in the United States.

Patients with alcohol-associated liver disease have traditionally needed to demonstrate an ability to refrain from drinking for 6 months before being deemed eligible for a liver transplant, despite the absence of research findings to support this requirement. Findings from this retrospective study show that a waiting period is not associated with improved outcomes.