Buspirone (Buspar) is approved for generalized anxiety disorder, but its efficacy there is often questioned. Here we find out how it stacks up against the benzos and SSRIs, and explore its off-label potential in depression, sexual dysfunction, alcoholism, traumatic brain injury, and premenstrual dysphoric disorder.

People can still find meaningful lives even in with the most debilitating medical disorders, including locked in syndrome. In this neurologic disorder, patients maintain full awareness but are unable to speak or move due to complete paralysis of nearly all voluntary muscles in the body.

When researchers at the Department of Veteran Affairs found a 61% increase in suicide attempts when veterans took trazodone vs. zolpidem for sleep, the story made headlines. We tease apart the strengths and weaknesses of this 350,000 subject study to see what the real risk is.