Sin Yan Lo, PMHNP-BC. Ms. Lo has no financial relationships with companies related to this material.

Kamron Fariba, DO. Dr. Fariba has no financial relationships with companies related to this material.

Michael Posternak, MD. Dr. Posternak has no financial relationships with companies related to this material.

Glen Spielmans, PhD. Dr. Spielmans has no financial relationships with companies related to this material.

Marilyn J. Vaché, MD. Dr. Vaché has no financial relationships with companies related to this material.

Margo C. Funk, MD, MA, FACLP.

Director of Cardiovascular Psychiatry, Vice Chair for Education, Residency Program Director, Department of Psychiatry, Brigham and Women’s Hospital, Boston, MA.

Dr. Funk has disclosed that in 2021, she received fees as a consultant for Acadia Pharmaceuticals. Dr. Aiken has reviewed this educational activity and has determined that there is no commercial bias as a result of this financial relationship.

“About half of older adults with depression have evidence of a vascular contribution [to the mood disorder] on MRI, and the rate goes up with age.”

Chris Aiken, MD. Editor-in-Chief of The Carlat Psychiatry Report; Assistant Professor, NYU Langone Department of Psychiatry; practicing psychiatrist, Winston-Salem, NC.

Dr. Aiken has no financial relationships with companies related to this material.

Bryan K. Tolliver, MD, PhD

Associate professor, Addiction Sciences Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina. Charleston, SC.

Dr. Tolliver has no financial relationships with companies related to this material.

“When tailoring medication choice, a careful history can guide you. If I’m treating a patient who drinks excessively at night to sleep or who struggles with insomnia when they try to stop drinking, I’ll start with a sedating antidepressant like mirtazapine. That’s not an evidence-based decision, it’s a clinical decision that I think can be helpful.”