After encouraging results in depression, the natural therapy palmitoylethanolamide (PEA) undergoes a randomized controlled trial in bipolar mania.

A survey of gun ownership and gun purchasing plans found that individuals with depressive symptoms were significantly more likely to purchase a gun, or plan to purchase a gun, compared to non-depressed individuals, especially during the COVID-19 pandemic.

Sublingual dexmedetomidine was found to work effectively and quickly for mild to moderate agitation in patients with bipolar disorder.

Peripartum mood problems are common, particularly for women with bipolar disorder. 

A large analysis raises questions about antidepressant efficacy in certain age groups, and also finds a sweet spot.

Lithium’s reputation as a difficult med may have more to do with branding than reality, according to this large analysis of mood stabilizer adherence.

This study made headlines with its surprising results, but you’ll want to read the fine print to understand how it informs practice.

Major depressive disorder, mood disorders, SSRIs, borderline personality disorder