In bipolar disorder, oxcarbazepine is slightly better tolerated than carbamazepine, but less effective. While its medical risks are different, they are by no means safer than carbamazepine’s. Its drug interactions can be a problem as well.

On average, higher doses of second-generation antidepressants do not bring greater recoveries in major depression, but they do cause a steep increase in side effects and dropouts.

A new antipsychotic and a new sleep medication are reviewed.