You've probably heard about Fanapt (iloperidone) and Saphris (asenapine), two antipsychotics that have recently won FDA approval for the acute treatment of schizophrenia, and, in the case of Saphris, for the treatment of manic and mixed episodes of bipolar disorder. Are these more “me too”...
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One of the most controversial topics for the DSM-V committee is whether to include a new diagnosis called Risk Syndrome for First Psychosis. Patients with schizophrenia commonly report a history of prodromal symptoms before developing the full-blown disorder...
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While we typically pick and choose among various drug classes to treat patients with borderline personality disorder (BPD), we have a hard time basing our choices on the evidence.
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Guanfacine, an alpha-2 agonist, is sometimes prescribed off-label for ADHD and has now received official FDA approval in a new, extended-release formulation. Shire will soon market the drug under the brand name Intuniv. So how well does it work?
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In order to test whether phone therapy is helpful as an adjunct to antidepressant medication, researchers enrolled 600 depressed outpatients in a randomized trial.
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Dr. Ongur, over the past few decades, the dominant theory of schizophrenia has been the dopamine hypothesis, but that has been changing lately. Can give us a quick review of the original hypothesis and then go on to some of the alternative neurochemical theories?
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Dr. Aiken is the Editor in Chief of The Carlat Psychiatry Report; director of the Mood Treatment Center in North Carolina, where he maintains a private practice combining medication and therapy along with evidence-based complementary and alternative treatments; and Assistant Professor NYU Langone Department of Psychiatry. He has worked as a research assistant at the NIMH and a sub-investigator on clinical trials, and conducts research on a shoestring budget out of his private practice. Follow him on Twitter and find him on LinkedIn.
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