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The Carlat Psychiatry Report

Medication Treatment of Depression (January) | 2006

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Paxil CR

January 1, 2003

Dr. Richard Naimark, a psychiatrist in private practice at Chestnut Hill Counseling in Dover, New Hampshire, relates a tidbit that tempers TCR’s fairly lukewarm review of Paxil CR. Read More

Dr. John O’Reardon on Treatment-Resistant Depression

January 1, 2003

John O'Reardon, MD

Dr. O’Reardon, I’d like to pick your mind about your approach to treatment resistant depression. First of all, how do you define it? Read More

Paxil CR: Paxil by any other name...

January 1, 2003

Daniel Carlat, MD

The latest member of the “controlled-release club” is GlaxoSmithKline, with its Paxil CR. While cynics may believe that CR launches are simply efforts to prolong patent-lives and therefore profits, the reality is that CR formulations are generally better tolerated and easier to dose. Read More

Lexapro: The Son of Celexa

January 1, 2003

Daniel Carlat, MD

Celexa (Citalopram) has been used in Europe since the late 1980s, and since its introduction in the U.S. market in 1998 it has made steady inroads into the SSRI market, largely because it has the reputation of being unusually well tolerated. Read More

Effexor XR: Is it really as good as they say it is?

January 1, 2003

Daniel Carlat, MD

… psychiatric research standards, the numbers were huge: 851 patients in the Effexor XR group, 748 in the SSRI group (Prozac, Paxil, and Luvox), and 446 in the placebo group. The doses of comparator SSRIs were robust enough to mirror what we actually use in clinical practice, and treatment duration... Read More

St. John’s Wort: Wilting in America

January 1, 2003

Daniel Carlat, MD

America has not been kind to St. John’s Wort. In Europe, this flowering bush that blooms around June 24 (St. John’s Day), has been all the rage for about 2000 years. It was first mentioned by the Roman Pliny the Elder in the first century, and over the past two millennia it has been used for a variety of ills, including diarrhea, urinary problems, demonic exorcism, and more recently, for melancholia. Read More

The First Antidepressant

November 1, 2006

The first patient to receive a modern antidepressant was Paula J. F., a Swiss woman admitted to the Munsterlingen asylum with depression. Read More

Learning Objectives, The Use of MAOIs, TCPR, November 2006

November 1, 2006

After reading these articles, you should be able to… Read More

Medication Fact Book for Psychiatric Practice, Seventh Edition (2024)
The updated 2024 reference guide covering the most commonly prescribed medications in psychiatry.
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General Psychiatry
KarXT (Cobenfy): The Breakthrough Antipsychotic That Could Change Everything
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General Psychiatry
Psychopharm Secrets: What Patients Won’t Tell You
How to assess med response when the patient reports is a poor guide: long-term mood stabilizers, sleep meds, and rapid cycling.
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