New evidence suggests that the prevalence of fetal alcohol spectrum disorder is higher than previously documented. In this study, prevalence estimates were derived from 13,146 first-grade children in four U.S. communities between 2010 and 2016.

Since estrogen can affect neurotransmitter functioning, there has been some interest in using estrogen modulators to treat psychiatric conditions, including schizophrenia. Raloxifene is a selective estrogen receptor modulator (SERM) with some preliminary evidence for effectiveness in women with schizophrenia.

In this article, I’ll start by briefly outlining what the research tells us about the risks of substance use to the fetus. The more informed you are about these risks, the more persuasive and helpful you can be to patients. I’ll then move on to discussing how, as an OB/GYN, I approach the evaluation and treatment of these patients, emphasizing issues of interest to clinicians.

Typically, the most frequent problem that I’m referred is the pregnant patient who’s dependent on opioids. And this could be either someone who’s using illicit drugs, such as heroin, or is prescribed prescription opioids.

We’ve been hearing for some time now about the FDA’s plans to revise the long-standing categories A, B, C, D, and X designations for risk of using medications in pregnancy. The new rule (referred to as PLLR for Pregnancy and Lactation Labeling Rule) was proposed in 2008, finalized in 2014,...

We’ve been hearing for some time now about the FDA’s plans to revise the long-standing categories A, B, C, D, and X designations for risk of using medications in pregnancy. The new rule (referred to as PLLR for Pregnancy and Lactation Labeling Rule) was proposed in 2008, finalized in 2014, and implementation began during the summer of 2015.

Dr. Vivien Burt discusses mood disorders and pregnancy. It’s now pretty widely recognized that pregnancy does not protect against mental illness, and the postpartum period is certainly a time of very high vulnerability for women, especially if they’ve had a history of psychiatric illness.

Concerns about the safety of psychiatric medications during pregnancy are common among psychiatrists and patients alike. In many cases, one must weigh the risks of a medication to mother or child against the risks inherent in untreated mental illness. Recent research, however, lends support to the growing data about the safety of antidepressant medications in pregnancy.

The World Health Organization has released evidence-based guidelines for healthcare professionals to help pregnant women who abuse alcohol or other drugs.

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