Clinicians should understand how amphetamine and methylphenidate differ in respect to their: risks of psychosis, mania, and substance use, neurotoxic and neuroprotective properties, efficacy and tolerability, and use across the lifespan.
KarXT (Cobenfy) is the first antipsychotic that doesn’t block dopamine. We trace the origins of this new drug to a South Asian herb used for over 5,000 years, up to the three...