People with anorexia usually don’t want to take medications, but does pharmacotherapy even work? Not at all, concludes Emanuele Cassioli and colleagues in this new meta-analysis. [Link]Published On: 6/2/2020Duration: 1 minute, 51 secondsTranscript:People with anorexia usually don’t want to take medications, but does pharmacotherapy even work? Not at all, concludes...

People with profound disabilities are happier than we think, and the ways they adjust to their limitations tell us a lot about how to help people with chronic psychiatric illness.Published On: 6/1/20Duration: 16 minutes, 54 secondsGot Feedback? Take the podcast survey.

Today’s study was a randomized controlled trial comparing a self-guided online therapy to face-to-face CBT for health anxiety. Even if you’re not a therapist, stay tuned for a practical take-away at the end.Published on: 5/30/2020Duration: 2 minutes, 10 secondsTranscript:The study enrolled 204 patients with hypochondriasis.  Actually, they did not have...

Patients don’t just look to their health care providers for medications, they also turn to for wisdom in times of crisis. Dr. Ellen Lee and colleagues at the University of California San Diego speculate that wisdom could be a vaccination against several of the epidemics that continue to rise in...

Do they help? Do they harm? And can mood stabilizers protect patients who take them? A review of Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G. Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: A systematic review and network meta-analysis. J Affect...

Blueberries, walnuts, tea, salt, and the Mediterranean diet are featured in this playful but practical stroll through the latest research on food and the brain.Published On: 5/25/20Duration: 10 minutes, 1 secondsDiet for Depression: Vegetables (5 servings per day), fruits (2–3 per day), wholegrain cereals (3 per day), protein (lean meat, poultry, eggs,...

A new meta-analysis ranked all the medications for bipolar depression, and we found a surprise in the stack. A review of Bahji A, Ermacora D, Stephenson C, Hawken ER, Vazquez G. Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: A systematic review and network...

Obesity is rarely a harbinger of recovery with antidepressant therapy, but at least 3 treatments may be exceptions to that rule. A review of Freeman MP, Hock RS, Papakostas GI, et al. Body Mass Index as a Moderator of Treatment Response to Ketamine for Major Depressive Disorder. J Clin Psychopharmacol.

FDA strengthens warning on clozapine induced constipation. What do we do when it happens? And what does this mean for the rest of our psych meds? Dr. Jonathan Meyer explains.Published on: 5/18/20Duration: 14 minutes, 2 secondsArticle Referenced: "A Potentially Lethal Side Effect You Probably Never Heard Of," The Carlat Psychiatry Report,...

It's been a year since esketamine's (Spravato) debut for treatment resistant depression, and the numbers are in: to treat and to harm. A review of Citrome L, DiBernardo A, Singh J. 144 Esketamine Nasal Spray for Management of Treatment-Resistant Depression: Number Needed to Treat, Number Needed to Harm, Likelihood to...