This month the first systemic meta-analysis of epidemiologic studies of ultra processed foods has come out, and we have a clearer picture of what poor dietary habits do to 300,000 people. [Link]Published On: 11/7/2020Duration: 5 minutes, 34 secondsGot feedback? Take the podcast survey.

In 2004 Morgan Spurlock decided to see what would happen when he ate a typical McDonald’s meal for breakfast, lunch, and dinner. Over the next 30 days, we watched as he gained 24 pounds and developed high cholesterol, fatty liver, and signs of depression in the now classic documentary Supersize...

The FDA keeps recalling medications for contamination with NDMA, and the contamination was recently found in the first-line antidote for antipsychotic weight gain: metformin.Published On: 11/2/2020Duration: 13 minutes, 13 secondsTranscript:Welcome to the Carlat Psychiatry Podcast, keeping psychiatry honest since 2003. I’m Chris Aiken, the editor in chief of the Carlat Report. And...

Chemicals from plastics, pesticides, and food processing are linked to ADHD, according to a new paper in JAMA Open Network. [Link]Published On: 10/31/2020Duration: 3 minutes, 1 secondGot feedback? Take the podcast survey.

Xyrem is a branded form of sodium oxybate, the sodium salt of gamma-hydroxybutyrate, or GHB , to precursor to GABA, glutamate, and glycine which is FDA approved for narcolepsy and cataplexy. The news on Xyrem is that the FDA just approved a new version of it – called Xywav – made...

We take you through the story of rational drug discovery that lead to the approval of guanfacine and clonidine for ADHD, and share some tips on how to use them. And the word of the day: Dyssymbole.Published On: 10/26/2020Duration: 19 minutes, 55 secondsArticle Referenced: "Guanfacine ER for Adults With ADHD?"...

The hand eye movements of a prescription video game are thought to exercise circuits involved in attention, and this theory did translate to small but real improvements in attention in 5 clinical trials involving over 600 children with ADHDPublished On: 10/24/2020Duration: 3 minutes, 4 secondsTranscript: A spaceman rides down an icy...

Last April we reported on Pimavenserin – Nuplazid – the novel antipsychotic that’s FDA approved in psychosis related to parkinson’s disease. In that article we mentioned a randomized controlled trial from Mass General – the CLARITY trial - that showed promising augmentation effects when Pimavenserin was added to an antidepressant...

We interview Ruta Nunacs on perimenopausal depression, and our word of the day – processomania – brings us into the crosshairs of politics and psychiatry.Published On: 10/18/20Duration: 24 minutes, 42 secondsArticle Referenced: "Mood and Menopause," The Carlat Psychiatry Podcast, October 2020Rough Transcript:Dr. Aiken: Women have twice the risk of depression as men. But...

New labeling from the FDA requires physicians to discuss naloxone with patients or caregivers they are prescribing opioids to. The new guideline also recommends that we prescribe naloxone to anyone who is at risk for opioid overdose, even if we aren’t prescribing them an opioid. That would include patients with...