Paul Riordan, MD.

Clinical Update

Negative Symptoms of Schizophrenia

January 1, 2024

Chris Aiken, MD. Editor-in-Chief, The Carlat Psychiatry Report. Assistant Professor, NYU Langone Department of Psychiatry. Practicing psychiatrist, Winston-Salem, NC.

Paul Riordan, MD. Assistant Consulting Professor of Psychiatry, Duke University, Durham, NC.

The authors have no financial relationships with companies related to this material.

Negative symptoms are the primary cause of disability in schizophrenia, and we identify a few antipsychotics and a few add-on therapies that can help.

RESEARCH UPDATE

Should We Use Two Antidepressants to Treat Unipolar Depression?

January 1, 2023

Paul Riordan, MD.

Paul Riordan, MD. Dr. Riordan has no financial relationships with companies related to this material.

Antidepressant combinations come up wanting in this meta-analysis, with one possible ray of hope.

Quetiapine Reconsidered

June 1, 2022

Paul Riordan, MD.

Paul Riordan, MD. Assistant Consulting Professor of Psychiatry, Duke University. Dr. Riordan has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

It is the best of drugs; it is the worst of drugs. Quetiapine (Seroquel) has a few benefits that are unmatched by other medications, and here we explore where it fits in depression, bipolar, schizophrenia, as well as off-label uses like anxiety and sleep.

A Review of Medications for PTSD, With a Focus on Topiramate

May 4, 2021

Paul Riordan, MD.

Paul Riordan, MD. Assistant Consulting Professor of Psychiatry, Duke University. Dr. Riordan has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Topiramate is not first-line in PTSD, but it does have a role, particularly when alcohol use is part of the picture.

CLINICAL UPDATE

Depression, Vitamin D, and COVID-19

May 4, 2021

Paul Riordan, MD.

Paul Riordan, MD. Assistant Consulting Professor of Psychiatry, Duke University. Dr. Riordan has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Vitamin D deficiency is causing everything from depression to cancer to COVID-19, at least that’s what our patients are hearing. Paul Riordan looks at the strength of that research and clarifies when to check levels and when to supplement.

How COVID-19 Affects the Brain

September 3, 2020

Paul Riordan, MD.

Paul Riordan, MD. Assistant Consulting Professor of Psychiatry, Duke University. Dr. Riordan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Pandemics create a long list of psychosocial stressors, but COVID-19 also has direct effects on the CNS. Neuropsychiatric syndromes can develop after the respiratory illness resolves. Paul Riordan reviews the cardinal symptoms to look for after a COVID infection.