Video games have come a long way since Pac Man and Tetris. Games today simulate reality in massive user-generated worlds.

We have an abundance of medications to treat depression, but “treatment resistance” remains all too common. Accordingly, there has been a rise in the number of “augmentation” or “adjunctive” medications to address this population.

Bipolar disorder presents unique pharmacologic challenges. Those treating children or adolescents with bipolar disorder face the additional challenge of having far less information to inform their treatment decisions.

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For decades, the principal treatment for substance use disorders has been psychological therapies. Twelve-step facilitation therapy, modeled after Alcoholics Anonymous, and motivational enhancement therapy are currently the two most widely used.Although disulfiram (Antabuse) hit the U.S. market in 1951, addiction pharmacotherapy was underwhelming for many years. Methadone (Dolophine) eventually arrived...

Alcoholics Anonymous (AA), the biggest self-help group for alcoholics not only in the United States but in the world, was founded in 1935 by Bill Wilson. Wilson—known as Bill W in keeping with the AA tradition of Anonymity—was a successful stockbroker who was also an alcoholic. He sought treatment in...

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Four new antipsychotics are beginning to gain some traction in the adult market. Here is a quick low down on paliperidone, iloperidone (Fanapt), lurasidone (Latuda), and asenapine (Saphris).