On July 10, the U.S. Food and Drug Administration (FDA) approved Otsuka and Lundbeck’s Rexulti (brexpiprazole) for schizophrenia and as an add-on to antidepressants for adults with depression. As the name suggests, it’s chemically and structurally related to aripiprazole (Abilify).

When we last reviewed neurostimulation devices 3 years ago, we concluded that there was some promise—but more sizzle than beef. Now there are more devices and more data. But is there more beef? Maybe.

Carly Simon swears by it. The daytime show “The Doctors” gave it a glowing review. Ads for it seem to be invading psychiatrists’ Google search results. We’re talking, of course, about the Fisher Wallace Stimulator and the similarly touted Alpha-Stim device. How do these devices work? Are they actually effective? And where do they fit into the rapidly expanding array of neuromodulators?

So let’s say you’ve decided to take the TMS plunge. With three devices currently FDA cleared, you have some decisions to make. The following table brings together some information you might find useful focusing on the Neronetics and Brainsway devices.

Mark George, MD started working on transcranial magnetic stimulation in 1993. In this interview he discusses the history of TMS and the state of trials and treatment options for patients 20 years later.

Dr. Williams discusses the field of interventional psychiatry from a practical standpoint by outlining the philosophy, practice, and case studies where interventional strategies have been effective.

Transitioning to high school can be a tough time, and studies have shown that teenagers are increasingly likely to have symptoms of depression over the course of their freshman year of school. Now an intriguing study seems to show that a simple intervention can ease these symptoms quite effectively.

Inflammation is hot, both literally and figuratively. The medical literature is replete with studies implicating inflammation as a possible root cause of diseases as varied as heart disease, cancer, Alzheimer’s disease, depression and, of course, arthritis. A recent meta-analysis of all randomized controlled studies for depression yielded some intriguing results.

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It is widely recognized that the death of a loved one commonly triggers intense sorrow and emotional pain. However, scientists have long known that there is more to grief than just sadness.Bereaved individuals can experience a range of emotions, cognitions, and behaviors following loss. Typical grief reactions can range from...