Depression in teenagers can present quite differently from both adults and younger kids. Can you help us to understand how to go about diagnosing depression in teens?

The debate over whether patients with bipolar disorder benefit from antidepressants rages on.

No clinician wants to be a “pill-pusher,” and most of our patients do not want that kind of treatment. So what can we offer our depressed patients beyond medications?

Are all psychotherapies equally effective for the treament of depression? Or do cognitive behavioral techniques clearly rise above the pack, as implied by the amount of media coverage they receive?

Dr. Hollon, your work as a psychologist and researcher focuses on the treatment and etiology of depression. What in particular do you study?

Dr. Raison, you are involved in some interesting research about the connections between inflammation and depression. Tell us about it.

Scopolamine is an anticholinergic most often used in patch form to prevent sea-sickness or post-surgical nausea. A recent double-blind, placebo-controlled trial looked at intravenous scopolamine’s effects as a treatment for unipolar depression.

Patients who don’t respond well to medication for depression are often referred for psychotherapy. But there has been little evidence that this actually works. A recent trial attempted to assess whether this method could help patients.

While tremor is traditionally thought of as a neurological issue, the symptom pops up often in psychiatric practice, and some basic knowledge of its diagnosis and treatment comes in handy.

It has long been thought that one’s genetic makeup combines with stressors to cause depression, but for many years there was little data to support this hypothesis.