Antidepressants - Articles - Page 3

How Essential Is Antidepressant Continuation?

June 1, 2022

Michael Posternak, MD. Dr. Posternak has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

A landmark study puts a spotlight on whether patients can successfully taper off their antidepressant without relapsing.

Tricyclic Antidepressants: When and How to Use Them

May 1, 2022

Edmund S. Higgins, MD. Clinical associate professor, Psychiatry and Behavioral Sciences, Medical University of South Carolina. Dr. Higgins has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Tricyclics have been used in psychiatry since the 1950s, when imipramine was introduced as the first mass-marketed antidepressant. Fluoxetine and the other SSRIs largely supplanted the tricyclics in the 1990s, but these medications still have their uses.

CLINICAL UPDATE

Antidepressants: When Dosage Matters

April 5, 2022

Rehan Aziz, MD.

Rehan Aziz, MD. Associate Professor of Psychiatry and Neurology, Rutgers Robert Wood Johnson Medical School. Dr. Aziz has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

When it comes to antidepressants, bigger is not better. Here we review the optimal dose ranges for antidepressants, describe how higher doses can worsen symptoms, and show you how to talk to patients about the issue.

Psilocybin vs Escitalopram for Depression

September 10, 2021

Michael Posternak, MD.

Michael Posternak, MD. Dr. Posternak has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Psilocybin is inching its way toward FDA approval in depression, but will this trial from the New England Journal of Medicine help it along or set it back?

Comparison of GI Side Effects of Antidepressants

August 3, 2021

Jesus Ligot, MD.

Jesus Ligot, MD. Dr. Ligot has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Modern antidepressants are ranked by their risk of GI side effects, with a few surprises baked in.

Antidepressants Harm Some With Bipolar Depression

March 26, 2021

Chris Aiken, MD.

Chris Aiken, MD. Dr. Aiken has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

This new study is the first placebo-controlled trial to examine the long-term effects of an SSRI in bipolar disorder.

How to Come Off a Psych Med Part 2: Antidepressants, Stimulants, and Benzos

March 11, 2021

Swapnil Gupta, MD

Swapnil Gupta, MD

Associate Professor at Icahn School of Medicine at Mount Sinai. Co-author of Deprescribing in Psychiatry (Oxford, 2019). Dr. Gupta has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

What do you do when a patient comes to you on a high dose of Adderall and Klonopin without any clear reason to be on them? Swapnil Gupta tackles this in part II of our interview on deprescribing, and describes how to fine-tune and microdose antidepressants and benzodiazepines to manage withdrawal symptoms.

How to Select an SSRI

November 12, 2020

Chris Aiken, MD.

Chris Aiken, MD. Editor-in-Chief of TCPR. Practicing psychiatrist, Winston-Salem, NC. Dr. Aiken has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

After digging through 3 decades of research, we can tell you this: There is no such thing as “the best” SSRI. But there are some important differences between them, and this article will show you how to find the right one for your patient.

EXPERT Q&A

Duty to Warn? Debating Antidepressant Suicidality

October 30, 2020

Martha J. Ignaszewski, MD and Glen Spielmans, PhD

Martha J. Ignaszewski, MD
Fellow, University of California, San Francisco

Glen Spielmans, PhD
Professor of Psychology, Metropolitan State University, St. Paul, MN

Dr. Ignaszewski and Dr. Spielmans have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.

For 16 years, since the FDA black box warning about suicidality with antidepressants, our community has been quoting data that downplays this concern. We were wrong. We were deceived. Antidepressants can be lifesaving, but there really is a duty to warn. Drs. Martha Ignazewski and Glen Speilmans talk with us about what went on and how to talk about it with our families.

Which Medications Have the Lowest Risk of Side Effects?

October 30, 2020

Pavan Madan, MD.

Pavan Madan, MD. Dr. Madan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

When we choose medications, we typically think that we are paying attention to risks and benefits. But what happens when we just look through the lens of side effects? An entirely different picture emerges of what medications might be the better picks. You will be surprised and intrigued by this review of a very helpful study that will probably change your prescribing patterns.