Do SSRIs and SNRIs cause bleeding? Several review articles have been published about it, and patients are beginning to ask us about it. What’s the scoop?

What’s new in antidepressant treatment? Not much.

In terms of starting new patients on antidepressants, PCPs do most of the prescribing.

It has been eight years since child psychiatry first began to deal with controversy about SSRIs and their potential to prompt suicidal behavior in youth.

Regular exercise can extend remission from major depression, regardless of whether remission was initially achieved through exercise or medication, a new study suggests.

Due to their inhibition of both serotonin and norepinephrine reuptake, the SNRIs venlafaxine (Effexor) and duloxetine (Cymbalta) have been billed as possessing an advantage over SSRIs.

The last time TCPR covered the topic of psychotropics in pregnancy was less than two years ago, in February of 2009. Since then, however, some new treatment guidelines have been published, and they appear to be useful to clinicians.

These new guidelines were issued jointly by our APA and by the American College of Obstetricians and Gynecologists. In addition to providing a nice summary of the neonatal risks of antidepressant exposure, the paper offers clear, concise, and easy to follow algorithms for the management of depression in three scenarios doctors are likely to encounter.

The Motherisk Program is a teratogen information service that has been around for more than 20 years.

SSRIs theoretically work by inhibiting the reuptake of serotonin, presumably by blocking the serotonin transporter pump whose job is to clean up excess serotonin in the synapses between neurons.