On February 8, 2007 the model and actress Anna Nicole Smith was found dead in her hotel room at the Seminole Hard Rock Hotel in Florida. An autopsy report ruled that the primary cause of death was a toxic overdose of several prescription medications, but most coverage has centered on chloral hydrate. Smith also had traces of Klonopin, Valium, Ativan, and Benadryl in her system, but the amounts of chloral hydrate were relatively high. Chloral hydrate is approved as sedative-hypnotic, but it should be used only for patients unresponsive to multiple trials of other hypnotics.