Antidepressants > Article

The Carlat Guide to Medications Used for Insomnia

This handy table lists the medications most often used to treat insomnia.

Sleeping Pills: Which Ones for Which Patients? [Subscribers Only]

Insomnia is one of the most common comorbidities you’ll see in your depressed and anxious patients. But it is often misunderstood. While the common view is that insomnia is caused by a primary psychiatric or medical condition, it is more accurate to simply say that patients have insomnia and depression at the same time. Insomnia is almost never an isolated problem.

Serotonergic Antidepressants and Abnormal Bleeding

Do SSRIs and SNRIs cause bleeding? Several review articles have been published about it, and patients are beginning to ask us about it. What’s the scoop?

Side Effect Management [Subscribers Only]

Let’s face it, dealing with side effects is not high on the list of “things we like most about psychiatry."

Four “New” Antidepressants. Or Are They? [Subscribers Only]

What’s new in antidepressant treatment? Not much.

Current APA/ACOG Recommendations for Managing Depression during Pregnancy in Three Scenarios

These new guidelines were issued jointly by our APA and by the American College of Obstetricians and Gynecologists. In addition to providing a nice summary of the neonatal risks of antidepressant exposure, the paper offers clear, concise, and easy to follow algorithms for the management of depression in three scenarios doctors are likely to encounter.

Antidepressant Treatment in Pregnancy: An Update [Subscribers Only]

The last time TCPR covered the topic of psychotropics in pregnancy was less than two years ago, in February of 2009. Since then, however, some new treatment guidelines have been published, and they appear to be useful to clinicians.

Alternative Treatments for Depression

No clinician wants to be a “pill-pusher,” and most of our patients do not want that kind of treatment. So what can we offer our depressed patients beyond medications?

Do Antidepressants Cause Switching?

The latest foray into the controversial issue of antidepressant-induced switching appeared in the February issue of The American Journal of Psychiatry (2006;163:232-239). The last time TCPR took up this topic (June 2005), we reviewed a meta-analysis of antidepressant use in bipolar disorder. That paper concluded that SSRIs cause the same rate of manic switching as placebo (Am J Psychiatry 2004;161:1537-1547). The authors of the newly published research would beg to differ.

Antidepressants: Does Mechanism Matter?

While it’s certainly interesting to theorize about neurotransmitters and antidepressants, the recent STAR*D findings bring up a difficult topic: Does mechanism matter?

How to Bring STAR*D Techniques into Your Practice

Because the first results from STAR*D make antidepressants look less powerful than we might have hoped, researchers have emphasized another aspect of the study – namely, that it represents a system that allows us to bring research techniques into our practices. A review of the STAR*D treatment manual is a useful exercise.

The STAR*D Trial: First Results

When National Public Radio’s Science Friday devotes most of a program to a psychiatric study, it must be newsworthy. The STAR*D study got this special treatment recently, with Ira Flato interviewing John Rush about the ins and outs of the NIMH-funded project.

VNS: Some Practical Information

If, after reviewing our admittedly lukewarm evaluation of the VNS data, you decide that you want to offer it to your patients, here’s some useful information.

FDA Approval of VNS: The All-Too-Human Side of a Bureaucracy

First they said yes to VNS, then no, then yes. And now they’re trying desperately to explain their final answer.

Vagus Nerve Stimulation: Is the Evidence Convincing?

Vagus nerve stimulation (VNS) is certainly new—but is it effective? It took the FDA a long time to make up its mind, but eventually it approved the treatment in May 2005. (For more details on why the FDA flip-flopped on the issue, see “FDA Approval of VNS,” this issue.) In this article, we scrutinize the two pivotal studies leading to approval.

Antidepressants > Article

The Carlat Guide to Medications Used for Insomnia

Sleeping Pills: Which Ones for Which Patients? [Subscribers Only]

Serotonergic Antidepressants and Abnormal Bleeding

Side Effect Management [Subscribers Only]

Four “New” Antidepressants. Or Are They? [Subscribers Only]

Current APA/ACOG Recommendations for Managing Depression during Pregnancy in Three Scenarios

Antidepressant Treatment in Pregnancy: An Update [Subscribers Only]

Alternative Treatments for Depression

Do Antidepressants Cause Switching?

Antidepressants: Does Mechanism Matter?

How to Bring STAR*D Techniques into Your Practice

The STAR*D Trial: First Results

VNS: Some Practical Information

FDA Approval of VNS: The All-Too-Human Side of a Bureaucracy

Vagus Nerve Stimulation: Is the Evidence Convincing?

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The 2011 TCPR Atypical Antipsychotics Table is Now Available!