Lamictal Fact Sheet
GlaxoSmithKline
Epilepsy in adults and children
- Delaying relapse to a mood episode in bipolar disorder in adults
- Off-label use as an antidepressant
Unknown.
Supplied in 25 mg, 100 mg, 150 mg, and 200 mg scored, breakable tablets; also in 2 mg, 5 mg, and 25 mg chewable tablets.
- Usual dosing is 25 mg QD X 1 week, then increase by 25 mg per week.
- Dosing with Depakote or in patients with a history of any drug rash: 12.5 mg X 1 week, then increase by 12.5 mg per week.
Stevens-Johnson Syndrome (a blistering flat rash that may affect the mucous membranes) occurs in about 1/5,000 patients, a risk not greater than with other anticonvulsants. In controlled trials for mood disorders, no cases of Stevens-Johnson occurred out of 1198 patients.
- Benign rash occurs in about 8% of patients, no more than placebo in most trials.
- Other side effects that occur at a rate greater than placebo, from most to least common: dizziness, headache, nausea, sedation.
Depakote doubles Lamictal levels
- Tegretol, Dilantin, Phenobarbital all decrease Lamictal levels by 40%
Current Issue
Topics
Search
Follow Us
Earn CME Credit Instantly!
Not quite ready for a one-year subscription to The Carlat Psychiatry Report? Need CME credits on a particular topic or on a tight deadline?
Try our A la Carte CME! You can buy single or multiple credits of continuing education, without committing to a year-long newsletter subscription.
Click here to purchase A la Carte CME credits
Already an A la Carte subscriber? Click here to go to your a la carte page
Steve Balt Interviewed by NPR
Our own Steve Balt was interviewed on NPR's "Talk of the Nation" on psychiatry's shift toward drugs and away from talk therapy.
Editor-in-Chief
After 10 years at the helm of TCPR, Dr. Carlat has handed over editor-in-chief duties to Dr. Steve Balt. We’re excited to welcome him aboard! Read More...
The 2012 Carlat Atypical Antipsychotics Table is Now Available!
With all the atypicals on the market, it's hard to keep track of indications, dosages, and all the other relevant facts for each drug. Use this table for summaries on these meds, their uses, their side effects, and a whole slew of other information.
TCPR Continuing Education
Accredited/Approved/Accepted by:
- ACCME
- AMA
- APA
- ABPN
- ANCC
- AAPA